Importance Evidence of gut microbiota perturbations has accumulated for multiple
psychiatric disorders, with microbiota signatures proposed as potential biomarkers …

Background More than 10 years have elapsed since human papillomavirus (HPV)
vaccination was implemented. We did a systematic review and meta-analysis of the …

Testing in school is usually done for purposes of assessment, to assign students grades
(from tests in classrooms) or rank them in terms of abilities (in standardized tests). Yet tests …

Purpose: Generation of a reactive stroma environment occurs in many human cancers and
is likely to promote tumorigenesis. However, reactive stroma in human prostate cancer has …

T-cell expression of programmed death receptor-1 (PD-1) down-regulates the immune
response against malignancy by interacting with cognate ligands (eg, PD-L1) on tumor cells; …

TRPM7 is a polypeptide with intrinsic ion channel and protein kinase domains whose
targeted deletion causes cells to experience growth arrest within 24 hr and eventually die …

Summary Background The WHO Director-General has issued a call for action to eliminate
cervical cancer as a public health problem. To help inform global efforts, we modelled …

Background WHO is developing a global strategy towards eliminating cervical cancer as a
public health problem, which proposes an elimination threshold of four cases per 100 000 …

Our understanding of the microbial involvement in inflammatory bowel disease (IBD)
pathogenesis has increased exponentially over the past decade. The development of newer …

Summary Background In 2007, Australia was one of the first countries to introduce a national
human papillomavirus (HPV) vaccination programme, and it has since achieved high …