User profiles for "author:Laura Brunelli"
Laura BrunelliIstiututo di Ricerche Farmacologiche Mario Negri IRCCS Verified email at marionegri.it Cited by 1769 |
Hippuric acid: Could became a barometer for frailty and geriatric syndromes?
G De Simone, C Balducci, G Forloni, R Pastorelli… - Ageing Research …, 2021 - Elsevier
Aging is a natural biological event that has some downsides such as increased frailty,
decline in cognitive and physical functions leading to chronical diseases, and lower quality …
decline in cognitive and physical functions leading to chronical diseases, and lower quality …
[HTML][HTML] Mortality prediction in patients with severe septic shock: a pilot study using a target metabolomics approach
Septic shock remains a major problem in Intensive Care Unit, with high lethality and high-
risk second lines treatments. In this preliminary retrospective investigation we examined …
risk second lines treatments. In this preliminary retrospective investigation we examined …
[HTML][HTML] Implication of metabolism in the polarization of tumor-associated-macrophages: the mass spectrometry-based point of view
G De Simone, C Soldani, A Morabito… - Frontiers in …, 2023 - frontiersin.org
Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune
cell types and are generally categorized into either of two functionally contrasting subtypes …
cell types and are generally categorized into either of two functionally contrasting subtypes …
[HTML][HTML] Capturing the metabolomic diversity of KRAS mutants in non-small-cell lung cancer cells
L Brunelli, E Caiola, M Marabese, M Broggini… - Oncotarget, 2014 - ncbi.nlm.nih.gov
In non-small-cell lung cancer (NSCLC), one-fifth of patients have KRAS mutations, which are
considered a negative predictive factor to first-line therapy. Evidence is emerging that not all …
considered a negative predictive factor to first-line therapy. Evidence is emerging that not all …
Protection of brain injury by amniotic mesenchymal stromal cell-secreted metabolites
Objectives: To define the features of human amniotic mesenchymal stromal cell secretome
and its protective properties in experimental models of acute brain injury. Design …
and its protective properties in experimental models of acute brain injury. Design …
[HTML][HTML] Correlation between eHealth literacy and health literacy using the eHealth literacy scale and real-life experiences in the health sector as a proxy measure of …
P Del Giudice, G Bravo, M Poletto, A De Odorico… - Journal of medical …, 2018 - jmir.org
Background The eHealth Literacy Scale (eHEALS) is a tool for the self-assessment of
perceived comfort and skills in using the internet as a source for health-related information …
perceived comfort and skills in using the internet as a source for health-related information …
[HTML][HTML] Prevalence of depressive symptoms among Italian medical students: The multicentre cross-sectional “PRIMES” study
F Bert, G Lo Moro, A Corradi, A Acampora, A Agodi… - PloS one, 2020 - journals.plos.org
Background Four percent of the world's population suffers from depression, which is a major
public health issue. Medical students are at risk, as their depressive symptoms (DS) …
public health issue. Medical students are at risk, as their depressive symptoms (DS) …
[HTML][HTML] Sustainable development goals and 2030 agenda: Awareness, knowledge and attitudes in nine Italian universities, 2019
C Smaniotto, C Battistella, L Brunelli, E Ruscio… - International journal of …, 2020 - mdpi.com
Sustainable Development Goals (SDGs) and 2030 Agenda represent global development
programs. Education can widen the acknowledgement of their relevance and their …
programs. Education can widen the acknowledgement of their relevance and their …
[HTML][HTML] Inhibition of the hexosamine biosynthetic pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis
F Ricciardiello, G Votta, R Palorini, I Raccagni… - Cell death & …, 2018 - nature.com
Cancer aberrant N-and O-linked protein glycosylation, frequently resulting from an
augmented flux through the Hexosamine Biosynthetic Pathway (HBP), play different roles in …
augmented flux through the Hexosamine Biosynthetic Pathway (HBP), play different roles in …
[HTML][HTML] Characterization of a metabolomic profile associated with responsiveness to therapy in the acute phase of septic shock
The early metabolic signatures associated with the progression of septic shock and with
responsiveness to therapy can be useful for developing target therapy. The Sequential …
responsiveness to therapy can be useful for developing target therapy. The Sequential …