User profiles for "author:Laura Brunelli"

Laura Brunelli

Istiututo di Ricerche Farmacologiche Mario Negri IRCCS
Verified email at marionegri.it
Cited by 1769

Hippuric acid: Could became a barometer for frailty and geriatric syndromes?

G De Simone, C Balducci, G Forloni, R Pastorelli… - Ageing Research …, 2021 - Elsevier
Aging is a natural biological event that has some downsides such as increased frailty,
decline in cognitive and physical functions leading to chronical diseases, and lower quality …

[HTML][HTML] Mortality prediction in patients with severe septic shock: a pilot study using a target metabolomics approach

M Ferrario, A Cambiaghi, L Brunelli, S Giordano… - Scientific reports, 2016 - nature.com
Septic shock remains a major problem in Intensive Care Unit, with high lethality and high-
risk second lines treatments. In this preliminary retrospective investigation we examined …

[HTML][HTML] Implication of metabolism in the polarization of tumor-associated-macrophages: the mass spectrometry-based point of view

G De Simone, C Soldani, A Morabito… - Frontiers in …, 2023 - frontiersin.org
Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune
cell types and are generally categorized into either of two functionally contrasting subtypes …

[HTML][HTML] Capturing the metabolomic diversity of KRAS mutants in non-small-cell lung cancer cells

L Brunelli, E Caiola, M Marabese, M Broggini… - Oncotarget, 2014 - ncbi.nlm.nih.gov
In non-small-cell lung cancer (NSCLC), one-fifth of patients have KRAS mutations, which are
considered a negative predictive factor to first-line therapy. Evidence is emerging that not all …

Protection of brain injury by amniotic mesenchymal stromal cell-secreted metabolites

F Pischiutta, L Brunelli, P Romele, A Silini… - Critical care …, 2016 - journals.lww.com
Objectives: To define the features of human amniotic mesenchymal stromal cell secretome
and its protective properties in experimental models of acute brain injury. Design …

[HTML][HTML] Correlation between eHealth literacy and health literacy using the eHealth literacy scale and real-life experiences in the health sector as a proxy measure of …

P Del Giudice, G Bravo, M Poletto, A De Odorico… - Journal of medical …, 2018 - jmir.org
Background The eHealth Literacy Scale (eHEALS) is a tool for the self-assessment of
perceived comfort and skills in using the internet as a source for health-related information …

[HTML][HTML] Prevalence of depressive symptoms among Italian medical students: The multicentre cross-sectional “PRIMES” study

F Bert, G Lo Moro, A Corradi, A Acampora, A Agodi… - PloS one, 2020 - journals.plos.org
Background Four percent of the world's population suffers from depression, which is a major
public health issue. Medical students are at risk, as their depressive symptoms (DS) …

[HTML][HTML] Sustainable development goals and 2030 agenda: Awareness, knowledge and attitudes in nine Italian universities, 2019

C Smaniotto, C Battistella, L Brunelli, E Ruscio… - International journal of …, 2020 - mdpi.com
Sustainable Development Goals (SDGs) and 2030 Agenda represent global development
programs. Education can widen the acknowledgement of their relevance and their …

[HTML][HTML] Inhibition of the hexosamine biosynthetic pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis

F Ricciardiello, G Votta, R Palorini, I Raccagni… - Cell death & …, 2018 - nature.com
Cancer aberrant N-and O-linked protein glycosylation, frequently resulting from an
augmented flux through the Hexosamine Biosynthetic Pathway (HBP), play different roles in …

[HTML][HTML] Characterization of a metabolomic profile associated with responsiveness to therapy in the acute phase of septic shock

A Cambiaghi, BB Pinto, L Brunelli, F Falcetta, F Aletti… - Scientific reports, 2017 - nature.com
The early metabolic signatures associated with the progression of septic shock and with
responsiveness to therapy can be useful for developing target therapy. The Sequential …