User profiles for "author:Joseph Mikhael"

Joseph Mikhael

Professor, TGen (Translational Genomics Research Institute), City of Hope Cancer Center
Verified email at myeloma.org
Cited by 15825

Role of 18F-FDG PET/CT in the diagnosis and management of multiple myeloma and other plasma cell disorders: a consensus statement by the International …

M Cavo, E Terpos, C Nanni, P Moreau… - The lancet …, 2017 - thelancet.com
Summary The International Myeloma Working Group consensus aimed to provide
recommendations for the optimal use of 18 fluorodeoxyglucose (18 F-FDG) PET/CT in …

Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus …

SK Kumar, JR Mikhael, FK Buadi, D Dingli… - Mayo Clinic …, 2009 - Elsevier
Multiple myeloma is a malignant plasma cell neoplasm that affects more than 20,000 people
each year and is the second most common hematologic malignancy. It is part of a spectrum …

Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group

P Moreau, SK Kumar, J San Miguel, F Davies… - The Lancet …, 2021 - thelancet.com
Summary This Policy Review presents the International Myeloma Working Group's clinical
practice recommendations for the treatment of relapsed and refractory multiple myeloma …

Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus …

JR Mikhael, D Dingli, V Roy, CB Reeder, FK Buadi… - Mayo Clinic …, 2013 - Elsevier
Multiple myeloma remains an incurable neoplasm of plasma cells that affects more than
20,000 people annually in the United States. There has been a veritable revolution in this …

Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): a multicentre, open-label, randomised phase 3 trial

P Moreau, MA Dimopoulos, J Mikhael, K Yong… - The Lancet, 2021 - thelancet.com
Background Isatuximab is an anti-CD38 monoclonal antibody approved in combination with
pomalidomide–dexamethasone and carfilzomib–dexamethasone for relapsed or refractory …

Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial

CB Reeder, DE Reece, V Kukreti, C Chen, S Trudel… - Leukemia, 2009 - nature.com
We have studied a three-drug combination with cyclophosphamide, bortezomib and
dexamethasone (CyBorD) on a 28-day cycle in the treatment of newly diagnosed multiple …

Efficacy of venetoclax as targeted therapy for relapsed/refractory t (11; 14) multiple myeloma

S Kumar, JL Kaufman, C Gasparetto… - Blood, The Journal …, 2017 - ashpublications.org
Venetoclax is a selective, orally bioavailable BCL-2 inhibitor that induces cell death in
multiple myeloma (MM) cells, particularly in those harboring t (11; 14), which express high …

Cyclophosphamide-bortezomib-dexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis

JR Mikhael, SR Schuster… - Blood, The Journal …, 2012 - ashpublications.org
Cyclophosphamide, bortezomib, and dexamethasone (CyBorD) is highly effective in multiple
myeloma. We treated patients with light chain amyloidosis (AL) before stem cell …

Pomalidomide alone or in combination with low-dose dexamethasone in relapsed and refractory multiple myeloma: a randomized phase 2 study

PG Richardson, DS Siegel, R Vij… - Blood, The Journal …, 2014 - ashpublications.org
This multicenter, open-label, randomized phase 2 study assessed the efficacy and safety of
pomalidomide (POM) with/without low-dose dexamethasone (LoDEX) in patients with …

[PDF][PDF] Pomalidomide (CC4047) plus low-dose dexamethasone as therapy for relapsed multiple myeloma

MQ Lacy, SR Hayman, MA Gertz, A Dispenzieri… - J Clin …, 2009 - researchtopractice.com
Pomalidomide (CC4047) Plus Low-Dose Dexamethasone as Therapy for Relapsed Multiple
Myeloma Page 1 Pomalidomide (CC4047) Plus Low-Dose Dexamethasone as Therapy for …